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Mathias Wilhelms

Dr.-Ing. Mathias Wilhelms

Alumnus


Forschungsprojekt
Titel Ansprechpartner


Abgeschlossene Bachelor- oder Masterarbeiten
Titel Typ Bearbeiter Betreuer
Bachelorarbeit

Vanessa Lupici-Baltzer 

Studienarbeit

Franziska Grimm

Masterarbeit

Axel Loewe 

Studienarbeit

Lukas Holl

Bachelorarbeit

Hanne Hettmann

Bachelorarbeit

Niko Konrad

Bachelorarbeit

Yannick Lutz

Studienarbeit

Stefan Ponto

Diplomarbeit

Mathias Wilhelms

Studienarbeit

Mathias Wilhelms

Bachelorarbeit

Axel Loewe

Diplomarbeit

Jochen Schmid



Journal Articles (12)

M. Wilhelms, H. Hettmann, M. M. C. Maleckar, J. T. Koivumäki, O. Dössel, and G. Seemann.
Benchmarking electrophysiological models of human atrial myocytes.
In Frontiers in Physiology, vol. 3(487) , pp. 1-16, 2013
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M. Wilhelms, L. P. Holl, O. Dössel, and G. Seemann.
Impact of antiarrhythmic drugs on a virtual model of atrial fibrillation.
In Biomedizinische Technik / Biomedical Engineering, vol. 57 Suppl 1, 2012
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M. Wilhelms, C. Rombach, E. P. Scholz, O. Doessel, and G. Seemann.
Impact of amiodarone and cisapride on simulated human ventricular electrophysiology and electrocardiograms.
In Europace, vol. 14, pp. v90-v96, 2012
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M. Wilhelms, O. Dössel, and G. Seemann.
In silico investigation of electrically silent acute cardiac ischemia in the human ventricles.
In IEEE Transactions on Biomedical Engineering, vol. 58(10) , pp. 2961-2964, 2011
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A. Loewe, M. Wilhelms, J. Schmid, M. J. Krause, F. Fischer, D. Thomas, E. P. Scholz, O. Dössel, and G. Seemann.
Parameter estimation of ion current formulations requires hybrid optimization approach to be both accurate and reliable.
In Frontiers in Bioengineering and Biotechnology, vol. 3, pp. 209, 2016
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M. Keller, S. Schuler, M. Wilhelms, G. Lenis, G. Seemann, C. Schmitt, O. Dössel, and A. Luik.
Characterization of radiofrequency ablation lesion development based on simulated and measured intracardiac electrograms.
In IEEE Transactions on Biomedical Engineering, vol. 61(9) , pp. 2467-2478, 2014
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A. Loewe, Y. Lutz, M. Wilhelms, D. Sinnecker, P. Barthel, E. P. Scholz, O. Dossel, G. Schmidt, and G. Seemann.
In-silico assessment of the dynamic effects of amiodarone and dronedarone on human atrial patho-electrophysiology.
In Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology, vol. 16(suppl 4) , pp. iv30-iv38, 2014
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A. Loewe, W. H. W. Schulze, Y. Jiang, M. Wilhelms, A. Luik, O. Dössel, and G. Seemann.
ECG-Based Detection of Early Myocardial Ischemia in a Computational Model: Impact of Additional Electrodes, Optimal Placement, and a New Feature for ST Deviation.
In BioMed Research International Article, vol. 2015, pp. 530352, 2014
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A. Loewe, M. Wilhelms, F. Fischer, E. P. Scholz, O. Dössel, and G. Seemann.
Arrhythmic potency of human ether-a-go-go-related gene mutations L532P and N588K in a computational model of human atrial myocytes.
In Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology, vol. 16(3) , pp. 435-443, 2014
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E. P. Scholz, P. Carrillo-Bustamante, F. Fischer, M. Wilhelms, E. Zitron, O. Dössel, H. A. Katus, and G. Seemann.
Rotor termination is critically dependent on kinetic properties of I kur inhibitors in an in silico model of chronic atrial fibrillation.
In PloS one, vol. 8(12) , pp. e83179, 2013
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O. Dössel, M. W. Krueger, F. M. Weber, M. Wilhelms, and G. Seemann.
Computational modeling of the human atrial anatomy and electrophysiology.
In Medical & Biological Engineering & Computing, vol. 50(8) , pp. 773-799, 2012
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G. Seemann, D. U. J. Keller, M. W. Krueger, F. M. Weber, M. Wilhelms, and O. Dössel.
Electrophysiological modeling for cardiology: methods and potential applications.
In Information Technology, vol. 52(5) , pp. 242-249, 2010
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Book Chapters (1)

G. Seemann, M. W. Krueger, and M. Wilhelms.
Elektrophysiologische Modellierung und Virtualisierung für die Kardiologie - Methoden und potenzielle Anwendungen.
In Der virtuelle Patient, W. Niederlag, H. Lemke, H. Lehrach (eds), Health Academy, pp. 98-116, 2012
  

Conference Contributions (13)

M. Wilhelms, J. Schmid, M. J. Krause, N. Konrad, J. Maier, E. P. Scholz, V. Heuveline, O. Dössel, and G. Seemann.
Calibration of human cardiac ion current models to patch clamp measurement data.
In Computing in Cardiology, vol. 39, pp. 229-232, 2012
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M. Wilhelms, O. Dössel, and G. Seemann.
Comparing Simulated Electrocardiograms of Different Stages of Acute Cardiac Ischemia.
In FIMH 2011, LNCS, vol. 6666, pp. 11-19, 2011
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M. Wilhelms, O. Dössel, and G. Seemann.
Simulating the Impact of the Transmural Extent of Acute Ischemia on the Electrocardiogram.
In Computing in Cardiology, vol. 37, pp. 13-16, 2010
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M. Wilhelms, G. Seemann, M. Weiser, and O. Dössel.
Benchmarking Solvers of the Monodomain Equation in Cardiac Electrophysiological Modeling.
In Biomedizinische Technik / Biomedical Engineering, vol. 55(s1) , pp. 99-102, 2010
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M. Wilhelms, G. Seemann, and O. Dössel.
Benchmarking different models describing sinus node heterogeneity.
In IFMBE Proceedings, vol. 22, pp. 2691-2694, 2008
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A. Loewe, Y. Lutz, M. Wilhelms, D. Sinnecker, P. Barthel, E. P. Scholz, O. Dössel, G. Schmidt, and G. Seemann.
In-silico Assessment of the Dynamic Effects of Amiodarone and Dronedarone on Human Atrial Patho-Electrophysiology.
In Cardiac Physiome Workshop, 2015
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A. Loewe, Y. Lutz, M. Wilhelms, E. P. Scholz, O. Dössel, and G. Seemann.
Optimization of pharmacotherapy for familial atrial fibrillation in a numerical model of human atrial electrophysiology.
In Computing in Cardiology, vol. 41, pp. 745-748, 2014
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A. Loewe, M. Wilhelms, O. Dössel, and G. Seemann.
Influence of chronic atrial fibrillation induced remodeling in a computational electrophysiological model.
In Biomedizinische Technik / Biomedical Engineering, vol. 59(S1) , pp. S929-S932, 2014
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A. Loewe, M. Wilhelms, F. Fischer, E. P. Scholz, O. Dössel, and . Seemann G..
Impact of hERG Mutations on Simulated Human Atrial Action Potentials.
In Biomedizinische Technik/Biomedical Engineering, vol. 58(s1) , 2013
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A. Loewe, M. Wilhelms, J. Schmid, M. J. Krause, F. Fischer, E. P. Scholz, O. Dössel, and G. Seemann.
A Hybrid Optimization Approach for the Adaptation of Cardiac Ion Current Formulations to Voltage and Patch Clamp Data.
In Cardiac Physiome Workshop, 2013
G. Seemann, M. Alvarez de Eulate, N. Konrad, J. Maier, M. Wilhelms, D. Keller, O. Dössel, and E. Scholz.
Evaluating body surface ECG differences of simulated long-QT syndromes.
2013
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A. Loewe, W. H. W. Schulze, Y. Jiang, M. Wilhelms, and O. Dössel.
Determination of optimal electrode positions of a wearable ECG monitoring system for detection of myocardial ischemia: a simulation study.
In Computing in Cardiology, vol. 38, pp. 741-744, 2011
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G. Seemann, P. Carrillo Bustamante, S. Ponto, M. Wilhelms, E. P. Scholz, and O. Dössel.
Atrial fibrillation-based electrical remodeling in a computer model of the human atrium.
In Proc. Computing in Cardiology, vol. 37, pp. 417-420, 2010
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Alle Veröffentlichungen, sortiert nach Jahren

          2011 2010 2009 2008 [Alle]

Preise

Preis für das beste Doktorandenposter im Rahmen des Cardiac Physiome Workshop in Bar Harbor, USA, 2013
Axel Loewe, Mathias Wilhelms, Jochen Schmid, Mathias J. Krause, Fathima Fischer, Eberhard P. Scholz, Olaf Dössel, Gunnar Seemann
"A Hybrid Optimization Approach for the Adaptation of Cardiac Ion Current Formulations"

Preis für bestes Poster im Rahmen der Tagung Computers in Cardiology in Hangzhou: A. LoeweW. H. W. SchulzeYuan JiangM. WilhelmsO. Dössel
Determination of optimal electrode positions of a wearable ECG monitoring system for detection of myocardial ischemia: a simulation study; Computing in Cardiology, vol. 38, pp. 741 - 744, 2011