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Head of Institute:
Prof. Dr. rer. nat. Olaf Dössel 
Prof. Dr. rer. nat. Werner Nahm


Postal address:
Kaiserstr. 12
76131 Karlsruhe

Visitor / Delivery address:
Building 30.33
Fritz-Haber-Weg 1
76131 Karlsruhe

Fon: +49 721 608-42650
Fax: +49 721 608-42789
E-Mail: infoXxk4∂ibt kit edu

Presentations

At present no presentation is scheduled.

PersonalizeAF ITN

 

Looking for a PhD position to tackle atrial fibrillation with personalized approaches?

3 PhD student positions at IBT available within the Marie Skłodowska-Curie Innovative Training Network "PersonalizeAF". Apply by April 15!

[more]

Engineering for Health

Welcome to the web page of the Institute of Biomedical Engineering (IBT) at Karlsruhe Institute of Technology (KIT). For more than 50 years we have been active in research and teaching in the field of biomedical engineering.

In interdisciplinary projects together with medical doctors and medical industry, we investigate new technical systems that help to diagnose diseases earlier and more accurately as well as systems that make therapies more successful.

The main focus of the research program of Prof. Dr. Olaf Dössel is the analysis of biosignals from the heart (ECG and electrograms), the imaging of electrophysiological sources in the heart (ECG imaging). Moreover, we are working on impedance tomography for lung perfusion and hypothermia in stroke patients [more].

The area of research of Prof. Dr. Werner Nahm's group is optical systems in medicine and life sciences. Current projects are focussing on surgical visualization and optical diagnosis [more].

The group of Dr. Axel Loewe develops computational models of the heart and applies them to cardiological problems. We focus on cardiac electrophysiology and elastomechanics to contribute to answer clinical questions such as the genesis of e.g. cardiac arrhythmias and appropriate treatment strategies [more].

 

NEWS

Teaching and examinations at KIT temporarily suspended

The KIT will largely stop teaching and testing from March 17th. 2020 decided until April 19th. 2020 inclusive.
- Information on how the KIT Faculty ETIT deals with the changes in teaching and testing
- KIT NEWS: Questions and answers on how to deal with the corona virus
We ask you to write messages to the IBT secretary's office by email and not to appear in person.

 
openCARP
openCARP released

openCARP is an open cardiac electrophysiology simulator for in-silico experiments. Its source code is public and the software is freely available for academic purposes. openCARP is easy to use and offers single cell as well as multiscale simulations from ion channel to organ level. Additionally, openCARP includes a wide variety of functions for pre- and post-processing of data as well as visualization. The python-based CARPutils framework enables the user to develop and share simulation pipelines, i.e. automating in-silico experiments including all modeling/simulation steps.
openCARP is a joint effort of the Medical University of Graz (Gernot Plank), LIRYC Bordeaux (Ed Vigmond), U Freiburg (Gunnar Seemann) and KIT (Axel Loewe).

openCARP
 
Konferenz 2020-02-04
SPIE Photonics West

Two members of the IBT attended, presented two talks and shared their results on novel segmentation methods and a 3D microscale test target at the SPIE Photonics West Conference in San Francisco on the 01st February to 06th February. The useful feedback will be incorporated in further research and contact to possible new collaborates was set.

 
News 2020-01-30
What makes the heart beat?

The sinus node is the natural pacemaker of the heart initiating each heart beat. Its pacemaking function results from the interplay of to cooperating systems: the so-called membrane clock and the calcium clock. The precise role of these two mechanisms is incompletely understood. Together with a group of experimental researchers from Szeged (Hungrary), the Cardiac Modeling group could now further elucidate the role of the calcium clock. A novel pharmacological agent allows to specifically block the sodim-calcium exchanger. IBT researcher could reproduce and further investigate this effect mechanistically in a computational model. By combining experiment and computer simulation, the crucial role of the sodium-calcium exchanger and the interplay with the membrane clock could be consolidated. The study explains how the natural pacemaker of the heart becomes robust and reliable through the interplay of the two systems calcium clock and membrane clock.

More
 
dotnetpro 2020
Heart Simulator 1.0

The issue 1/2020 of the "dotnetpro“ journal features an article about the research of the cardiac modeling group. dotnetpro delivers expert knowledge for software developers, who use Microsoft technologies to write programs for Microsoft and non-Microsoft platforms. The idea behind the article is to provide a broader view for the dotnetpro readers, who mostly are software developers. The article introduces and describes the implementation of the multiscale simulation approach (from ion channels via cells and tissue up to the organ) for electrophysiology, which is developed and used at IBT. 

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TRM_2020
Towards the Digital Twin

Axel Loewe from IBT was invited to present at the 10th "TRM Forum on the Computer Simulation of Cardiac Function“. The meeting brings together leading experts on computational modeling, experimental assessment, and clinical research in the field of cardiac arrhythmias. We contributed to this year’s theme „Towards the Digital Twin“ by presenting work that allows to build a biomechanical twin of an individual patient. In addition, the session "Atrial modeling & experimental data" was chaired by the IBT researcher.

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