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Head of Institute:
Prof. Dr. rer. nat. Olaf Dössel 
Prof. Dr. rer. nat. Werner Nahm

Postal address:
Kaiserstr. 12
76131 Karlsruhe

Visitor / Delivery address:
Building 30.33
Fritz-Haber-Weg 1
76131 Karlsruhe

Fon: +49 721 608-42650
Fax: +49 721 608-42789
E-Mail: infoOte3∂ibt kit edu


At present no presentation is scheduled.

Engineering for Health

Welcome to the web page of the Institute of Biomedical Engineering (IBT) at Karlsruhe Institute of Technology (KIT). For more than 50 years we have been active in research and teaching in the field of biomedical engineering.

In interdisciplinary projects together with medical doctors and medical industry, we investigate new technical systems that help to diagnose diseases earlier and more accurately as well as systems that make therapies more successful.

The main focus of the research program of Prof. Dr. Olaf Dössel is the analysis of biosignals from the heart (ECG and electrograms), the imaging of electrophysiological sources in the heart (ECG imaging). Moreover, we are working on impedance tomography for lung perfusion and hypothermia in stroke patients [more].

The area of research of Prof. Dr. Werner Nahm's group is optical systems in medicine and life sciences. Current projects are focussing on surgical visualization and optical diagnosis [more].

The group of Dr. Axel Loewe develops computational models of the heart and applies them to cardiological problems. We focus on cardiac electrophysiology and elastomechanics to contribute to answer clinical questions such as the genesis of e.g. cardiac arrhythmias and appropriate treatment strategies [more].



Konferenz 2020-02-04
SPIE Photonics West

Two members of the IBT attended, presented two talks and shared their results on novel segmentation methods and a 3D microscale test target at the SPIE Photonics West Conference in San Francisco on the 01st February to 06th February. The useful feedback will be incorporated in further research and contact to possible new collaborates was set.

News 2020-01-30
What makes the heart beat?

The sinus node is the natural pacemaker of the heart initiating each heart beat. Its pacemaking function results from the interplay of to cooperating systems: the so-called membrane clock and the calcium clock. The precise role of these two mechanisms is incompletely understood. Together with a group of experimental researchers from Szeged (Hungrary), the Cardiac Modeling group could now further elucidate the role of the calcium clock. A novel pharmacological agent allows to specifically block the sodim-calcium exchanger. IBT researcher could reproduce and further investigate this effect mechanistically in a computational model. By combining experiment and computer simulation, the crucial role of the sodium-calcium exchanger and the interplay with the membrane clock could be consolidated. The study explains how the natural pacemaker of the heart becomes robust and reliable through the interplay of the two systems calcium clock and membrane clock.

dotnetpro 2020
Heart Simulator 1.0

The issue 1/2020 of the "dotnetpro“ journal features an article about the research of the cardiac modeling group. dotnetpro delivers expert knowledge for software developers, who use Microsoft technologies to write programs for Microsoft and non-Microsoft platforms. The idea behind the article is to provide a broader view for the dotnetpro readers, who mostly are software developers. The article introduces and describes the implementation of the multiscale simulation approach (from ion channels via cells and tissue up to the organ) for electrophysiology, which is developed and used at IBT. 

Towards the Digital Twin

Axel Loewe from IBT was invited to present at the 10th "TRM Forum on the Computer Simulation of Cardiac Function“. The meeting brings together leading experts on computational modeling, experimental assessment, and clinical research in the field of cardiac arrhythmias. We contributed to this year’s theme „Towards the Digital Twin“ by presenting work that allows to build a biomechanical twin of an individual patient. In addition, the session "Atrial modeling & experimental data" was chaired by the IBT researcher.

IMG_2019-11-08 DFG_News.jpg
DFG roundtable discussion on „Sustainability of Research Software in Germany“

On November 7 and 8, 40 members of the German research software community met at the Robert Koch institute in Berlin to work on a position paper on „Sustainability of Research Software in Germany“. On invitation of the DFG, the topics motivation for and selection of research software, funding, best practices, policies, and infrastructure were discussed. The respective demands, challenges, ideas for solutions were formulated and phrases as central recommendations for decision makers. After internal revision, the document will be made available to the public for discussion as part of the process for position papers of the German Society for Research Software Engineering (deRSE).

Atrial Signals 2019
Atrial Signals 2019 in Bordeaux

Six delegates of IBT attended the workshop Atrial Signals in Bordeaux on 14th and 15th October accompanied by their local clinical partners from Städtisches Klinikum Karlsruhe. Four years ago, the format of the workshop was called into being by Olaf Dössel and Claus Schmitt in Karlsruhe. It brings together physicians and engineers and creates a platform for the vivid exchange of needs, possibilities, and novelties in the context of working with signals from the human atria. Olaf Dössel contributed to the scientific program with two invited talks. Furthermore, IBT was represented with five posters. Laura Unger presented her work as one out of three finalists of the poster competition to the plenum.

The next workshop Atrial Signals will take place in Karlsruhe in 2021.