Institute of Biomedical Engineering

Effect of fibre orientation and bulk modulus on the electromechanical modelling of human ventricles

In collaboration with the group Modeling and Scientific Computing (MOX), at the Politecnico of Milan, the IBT researcher Luca Azzolin presented an electromechanical model of bi-ventricular human geometries and studied the influence of different fibre directions and incompressibility constraint and penalization on the compressibility of the material (bulk modulus) on the pressure-volume relation simulating a full heart beat. The paper showed how various fibre configurations and bulk modulus modified relevant clinical quantities such as stroke volume, ejection fraction and ventricle contractility.