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Tobias Oesterlein

Dr.-Ing. Tobias Oesterlein

Wissenschaftlicher Mitarbeiter
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Nach Vereinbarung. 


Raum: 413.1
Tel.: +49 721 608 - 47183
Fax: +49 721 608 - 42789
Tobias OesterleinMco2∂kit edu


Forschungsprojekte
Titel Ansprechpartner


Intracardial ECG Signal Processing / Mapping of endocardial activation patterns

Intracardial ECG Signal Processing / Mapping of endocardial activation patterns
Ansprechpartner:

Tobias Oesterlein, Olaf Dössel 

Projektgruppe:Medizinische Messtechnik &. digitale Signalverarbeitung

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Atrial Fibrillation (AFib) is the most common cardiac arrhythmia, showing an increasing prevalence with age. Hemodynamic impairment and thromboembolic events related to AFib result in significant morbidity and mortality.

PRJ_2011-02-16_C_Schilling_csc_Bild_01.jpg

Catheter ablation, notably the electric isolation of the pulmonary veins, has become a well-established curative therapeutic approach in drug-resistant atrial fibrillation. Despite the considerable clinical experience and accumulated evidence from experimental data, the exact mechanisms behind AFib are still not completely understood. Different concepts like rotational drivers, ectopic foci or dissociation of layers are discussed controversially - together with their respective curative ablation approaches.

PRJ_2011-02-16_C_Schilling_csc_Bild_02.jpg

Together with Städtisches Klinikum Karlsruhe, we are trying to understand endocardial activity during AFib. Electrograms measured intracardially during an electrophysiological examination are analyzed with methods of signal processing and multivariate statistics. A large set of descriptors can be computed for each signal and used to classify several different types of fractionated electrograms. The spatio-temporal pattern of excitation is evaluated using simultaneous multichannel data from catheters recording in local high-density or in panoramic mode with up to 64 electrodes. Quantitative analysis helps to identify dominant mechanisms and their degree of stability. All information can be visualized on patient specific geometries and related to the atrial anatomy. This will support the physician in finding the best ablation strategy in treatment of AFib.

Recent Publications

  • T. G. Oesterlein et al. Removing ventricular far-field signals in intracardiac electrograms during stable atrial tachycardia using the periodic component analysis, Journal of Electrocardiology, 48(2), pp. 171-180, 2015
  • C. Schilling et al. Fuzzy decision tree to classify complex fractionated atrial electrograms, BMT, 2015
  • F. M. Weber et al. Wave Direction and Conduction Velocity Analysis from Intracardiac Electrograms - A Single-Shot Technique. IEEE TBME (57), 2394-2401, 2010
Zu vergebende Arbeiten
Titel Typ Betreuer


Laufende Arbeiten
Titel Typ Bearbeiter Betreuer
Bachelorarbeit

Oliver Huhn

Masterarbeit

Daniel Frisch

Masterarbeit

Laura Unger

Bachelorarbeit

Michael Stritt



Abgeschlossene Arbeiten
Titel Typ Bearbeiter Betreuer
Studentische Forschungsarbeit

Salina Huck

Studentische Forschungsarbeit

Felix Plappert

Bachelorarbeit

Benedikt Ebener

Bachelorarbeit

Felix Plappert

Studentische Forschungsarbeit

Sophie An

Studentische Forschungsarbeit

Daniel Frisch

Masterarbeit

Franziska Schäuble

Bachelorarbeit

Salina Huck

Studentische Forschungsarbeit

Illya Grygoryev

Masterarbeit

Christian Reich

Masterarbeit

Alexander Kramlich

Bachelorarbeit

Johann Jazewitsch

Masterarbeit

Daniela Zöller

Masterarbeit

Niko Konrad

Bachelorarbeit

Julia Trächtler

Masterarbeit

Dan-Timon Rudolph

Bachelorarbeit

Daniel Frisch 

Bachelorarbeit

Fabian Schenkel

Masterarbeit

Markus Rottmann 

Studienarbeit

Tobias Oesterlein 



Veröffentlichungen


  Alle Veröffentlichungen, sortiert nach Jahren

          2016 2015 2014 2013 2012 2011 [Alle]

Journal Articles (8)

  • T. G. Oesterlein, J. Schmid, S. Bauer, A. Jadidi, C. Schmitt, O. Dössel, and A. Luik.
    Analysis and visualization of intracardiac electrograms in diagnosis and research: Concept and application of KaPAVIE.
  • In Computer Methods and Programs in Biomedicine, vol. 127, pp. 165-173, 2016

        [request PDF]  [doi]  


  • T. Oesterlein, D. Frisch, A. Loewe, G. Seemann, C. Schmitt, O. Dössel, and A. Luik.
    Basket-Type Catheters: Diagnostic Pitfalls caused by Deformation and Limited Coverage.
  • In BioMed Research International(Article ID 5340574) , pp. 1-13, 2016

        [request PDF]  [doi]  [url]  


  • T. G. Oesterlein, G. Lenis, D.-T. Rudolph, A. Luik, B. Verma, C. Schmitt, and O. Dössel.
    Removing ventricular far-field signals in intracardiac electrograms during stable atrial tachycardia using the periodic component analysis.
  • In Journal of Electrocardiology, vol. 48(2) , pp. 171-180, 2015

        [request PDF]  [doi]  


  • S. Pollnow, J. Greiner, T. Oesterlein, Eike M. Wülfers, A. Loewe, and O. Dössel.
    Mini Electrodes on Ablation Catheters: Valuable Addition or Redundant Information?—Insights from a Computational Study.
  • In Computational and Mathematical Methods in Medicine, vol. 2017(Article ID 168629) , pp. 13, 2017

        [request PDF]  [doi]  [url]  


  • O. Dössel, G. Lenis, A. Loewe, M. Rottmann, G. Seemann, and T. Oesterlein.
    Model Assisted Biosignal Analysis of Atrial Electrograms.
  • In Technisches Messen, vol. 83(2) , pp. 102-111, 2016

        [request PDF]  


  • G. Lenis, N. Pilia, T. Oesterlein, A. Luik, C. Schmitt, and O. Dössel.
    P wave detection and delineation in the ECG based on the phase free stationary wavelet transform and using intracardiac atrial electrograms as reference.
  • In Biomedizinische Technik. Biomedical Engineering, vol. 61(1) , pp. 37-56, 2016

        [request PDF]  [doi]  


  • C. Schilling, M. Keller, D. Scherr, T. Oesterlein, M. Haissaguerre, C. Schmitt, O. Dössel, and A. Luik.
    Fuzzy decision tree to classify complex fractionated atrial electrograms.
  • In Biomedizinische Technik. Biomedical Engineering, vol. 60(3) , pp. 245-255, 2015

        [request PDF]  [doi]  


  • J. E. Quijano, R. L. J. Campbell, T. G. Oesterlein, and L. M. Zurk.
    Experimental observations of active invariance striations in a tank environment.
  • In The Journal of the Acoustical Society of America, vol. 128(2) , pp. 611-618, 2010

        [request PDF]  [doi]  


Conference Contributions (16)

  • T. Oesterlein, A. Kramlich, G. Lenis, A. Luik, C. Schmitt, and O. Dössel.
    Automatic detection and mapping of double potentials in intracardiac electrograms.
  • In Current Directions in Biomedical Engineering, vol. 2(1) , pp. 179-183, 2016

        [request PDF]  


  • T. Oesterlein, G. Lenis, A. Luik, C. Schmitt, and O. Dössel.
    Optimized Approach for the Detection of Active Segments in Intracardiac Electrograms Measured during Atrial Flutter.
  • In 42nd International Congress on Electrocardiology Conference Book of Abstracts, 2015

        [request PDF]


  • T. Oesterlein, G. Lenis, A. Luik, B. Verma, C. Schmitt, and O. Dössel.
    Removing ventricular far field artifacts in intracardiac electrograms during stable atrial flutter using the periodic component analysis – proof of concept study.
  • In Proceedings 41th International Congress on Electrocardiology, pp. 49--52, 2014

        [request PDF]  


  • T. Oesterlein, G. Lenis, A. Luik, C. Schmitt, and O. Dössel.
    Periodic component analysis to eliminate ventricular far field artifacts in unipolar atrial electrograms of patients suffering from atrial flutter.
  • In Biomedizinische Technik / Biomedical Engineering, vol. 59(s1) , pp. 14, 2014

        [request PDF]


  • T. G. Oesterlein, M. W. Keller, S. Schuler, A. Luik, G. Seemann, C. Schmitt, and O. Dössel.
    Determination of local activation time in bipolar endocardial electrograms: a comparison of clinical criteria and a new method based on the non-linear energy operator.
  • In Journal of Electrocardiology, vol. 46(4) , pp. e18, 2013

        [request PDF]  [doi]  


  • T. G. Oesterlein, A. Luik, C. Schmitt, and O. Dössel.
    Generating biatrial local activation time maps using the non-linear energy operator reveals arrhythmia.
  • In Biomedizinische Technik. Biomedical Engineering, vol. 58(s1) , 2013

        [request PDF]  [doi]  


  • M. Stritt, T. Oesterlein, S. Pollnow, A. Luik, and C. Schmitt.
    Assessment of local high-density mapping for the analysis of radiofrequency ablation lesions in the left atrium.
  • In Current Directions in Biomedical Engineering, vol. 3(2) , pp. 109-112, 2017

        [request PDF]  [doi]  


  • G. Lenis, A. Kramlich, T. Oesterlein, A. Luik, C. Schmitt, and O. Dössel.
    Development and Benchmarking of Activity Detection Algorithms for Intracardiac Electrograms Measured During Atrial Flutter.
  • In Workshop Biosignal 2016. Innovation bei der Erfassung und Analyse bioelektrischer und bimagnetischer Signale, pp. 5-8, 2016

        [request PDF]


  • C. Reich, T. Oesterlein, M. Rottmann, G. Seemann, and O. Dössel.
    Classification of cardiac excitation patterns during atrial fibrillation.
  • In Current Directions in Biomedical Engineering, vol. 2(1) , pp. 161-166, 2016

        [request PDF]  


  • J. Greiner, T. Oesterlein, G. Lenis, and O. Dössel.
    Virtual-Reality Based Visualization of Cardiac Arrhythmias on Mobile Devices.
  • In Computing in Cardiology, 2016

        [request PDF]  


  • G. Lenis, T. Oesterlein, and O. Dössel.
    Orthogonal component analysis to remove ventricular far field in non periodic sustained atrial flutter.
  • In Computing in Cardiology, vol. 42, pp. 669-672, 2015

        [request PDF]  


  • J. Trächtler, Oesterlein T., A. Loewe, E. Poremba, A. Luik, C. Schmitt, and O. Dössel.
    Virtualizing clinical cases of atrial flutter in a fast marching simulation including conduction velocity and ablation scars.
  • In Current Directions in Biomedical Engineering, vol. 1(1) , pp. 405-408, 2015

        [request PDF]  [doi]  


  • O. Dössel, A. Luik, T. Oesterlein, M. Rottmann, B. Verma, and Schmitt C..
    Computer modeling of the atria and clinical electrograms.
  • In 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, vol. Poster Session, 2015

      [request PDF]  


  • A. Luik, T. Oesterlein, R. Wakili, K. Schmidt, H. Estner, A. Radzewitz, N. Horn, P. Hoermann, M. Merkel, G. Schymik, O. Dössel, and C. Schmitt.
    Coverage of the left atrial surface in patients with basket mapping for atrial fibrillation.
  • In Heart Rhythm On Demand 2014 - Poster Session II, vol. Lecture ID 5941, 2014

        [request PDF]  


  • M. Rottmann, T. Oesterlein, and O. Dössel.
    Local activation time based estimation of the direction of propagation of plane wave and the corresponding conduction velocity in simulated electrograms.
  • In Biomedizinische Technik / Biomedical Engineering, vol. 59(s1) , pp. 152-155, 2014

        [request PDF]  


  • M. Rottmann, M. W. Keller, T. Oesterlein, G. Seemann, and O. Dössel.
    Comparison of different methods and catheter designs to estimate the rotor tip position – a simulation study.
  • In Computing in Cardiology, vol. 41, pp. 133-136, 2014

        [request PDF]  




Preise

2017

2. Preis im Studentenwettbewerb, DGBMT und DGMP Jahrestagung 2017, Dresden;
M. Stritt, T. Oesterlein, S. Pollnow, A. Luik, and C. Schmitt.
Eingereichte Arbeit: Assessment of local high-density mapping for the analysis of radiofrequency ablation lesions in the left atrium.

 

2016

Auszeichnung bei der Konferenz „Computing in Cardiology“ 2016 in Vancouver (Kanada)
Bill and Gary Sanders Poster Award: Joachim Greiner, Tobias Oesterlein, Gustavo Lenis, Olaf Dössel: „Virtual Reality Visualization of Arrhythmias on a Smartphone“

2. Platz im Nachwuchswettbewerb im Rahmen des Workshop "Innovationen bei der Erfassung und Analyse bioelektrischer und biomagnetischer Signale - BBS 2016" durch Gustavo Lenis, Alexander Kramlich, Tobias Oesterlein and Olaf Dössel mit dem Beitrag: "Development and Benchmarking of Activity Detection Algorithms for Intracardiac Electrograms Measured During Atrial Flutter"

 

2014
Young Investigator Award im Rahmen der 41. Tagung International Congress on Electrocardiology in Bratislava, 2014.
T. G. Oesterlein, G. Lenis; A. Luik, B. Verma, C. Schmitt, O. Dössel
Eingereichte Arbeit: "Removing Ventricular Far Field Artifacts in Intracardiac Electrograms during Stable Atrial Flutter using the Periodic Component Analysis – Proof of Concept Study"

3. Preis im Studentenwettbewerb, DGBMT Jahrestagung 2014, Hannover,
T. G. Oesterlein, G. Lenis; A. Luik, C. Schmitt, O. Dössel
Eingereichte Arbeit: "Periodic component analysis to eliminate ventricular far field artifacts in unipolar atrial electrograms of patients suffering from atrial flutter"