News 2024
ImageCarmen Martínez Antón, PhD

Carmen Martínez Antón successfully defended her PhD thesis „Local Impedance Characterization for Scar and Fibrosis Detection – Towards a New Substrate Assessment for Atrial Mapping” on April 25th 2024. Our heartfelt congratulations!

ImageIBT present at DGK and EHRA 2024 Conferences

During April the conference of the German society of cardiology (DGK) and the European Heart Rhythm Association (EHRA) took place bringing together cardiologists from Germany and around the world. On the 7th-9th The European Heart Rhythm Association (EHRA) conference took place in Berlin. Our PhD student Patricia Martínez was nominated for the Young Investigator Award in the Basic and Translational Science category and presented her work on the effects of right atrial arrhythmia susceptibility in patient-specific computer models.

GAMM LogoIBT at the GAMM annual meeting 2024

From March 18 to March 22, 2024 the 94th annual meeting of the GAMM (Association of Applied Mathematics and Mechanics) took place in Magdeburg at the Otto von Guericke university. Our PhD student Jonathan Krauß presented a comparison of different pericardium modeling approaches.

ImageIBT at Biosignals Workshop Göttingen

In this year’s Biosignals Workshop in Göttingen, we presented our work on electrograms in a cell-by-cell model. We have shown that healthy excitation propagation, as opposed to what we would expect in homogenised models, yields asymmetric electrograms exhibiting several small deflections. These deflections, in turn, can be explained by the multimodality of cell activation as well as the deceleration of the excitation wave when transitioning between two cardiac cells.

ImageThe right atrium affects in silico arrhythmia vulnerability in both atria

What influence does the inclusion of the right atrium have on the assessment of arrhythmia susceptibility in patient-specific computer models? In this study, we investigated differences in arrhythmia susceptibility between monoatrial and biatrial models. Our results suggest that inclusion of the right atrium increases inducibility in the model and also shows a state-dependent influence on arrhythmia dynamics.

ImageNew Master Course “Medical Image Processing for guidance and navigation”

A new course for Master Students will be offered since SS24 from IBT lectures. The course, titled “Medical Image Processing for guidance and navigation”, will be worth 6 ECTs for a total of 4 hours per week of lectures/practical exercises plus the accomplishment of a group project.
The language of the lecture is English.

BildSoftware Carpentry Workshop at KIT

On March 19th and 20th 2024, the Institute of Biomedical Engineering is hosting an in person Software Carpentry workshop, primarily open to graduate students and research staff at KIT.

ImageToward Good Simulation Practice

This open access book has brought together 138 experts in In Silico Trials working in academia, the medical industry, regulatory bodies, hospitals, and consulting firms. Through a consensus process, these experts produced the first attempt to define some Good Simulation Practices on how to develop, evaluate, and use In Silico Trials.  Good Simulation Practice constitutes an indispensable guide for anyone who is planning to engage at any title with In Silico Trials. IBT researcher Axel Loewe has co-edited the chapters Model Development and The Investigator: Modellers and Analysts.

ImageKIT HealthTech at City Hall

On January 29, the KIT Center for Health Technologies presented itself to the Karlsruhe city society in the city hall. KIT Distinguished Senior Fellow Prof. Dössel gave a lecture on "Artificial Intelligence and Machine Learning in Medicine".

ImageNumerical evaluation of (electro-)mechanic cardiac models

Together with our collaborators at the Institute for Applied and Numerical Mathematics, we investigated the impact of modeling choices such as mesh size, incompressibility constraint, active strain or active stress as well as the choice of the damping scheme. Click here to learn about our findings:

ImageNew Research Associate at the IBT

The Institute of Biomedical Engineering welcomes Silvia Becker as a new research associate. Since January 2024, she has been working on the analysis of ECG data using machine learning within the “Computational Cardiac Modeling” research group.
Silvia Becker completed a master’s degree in electrical and information technology at the KIT. Her research topics focused on machine learning and heart simulations.

ImageDifferential effects of mechano-electric feedback mechanisms on whole-heart activation, repolarization, and tension

Which effects does the mechanical activation of the heart cause on the electrical control of cardiac rhythm and excitation? Using the fully coupled electro-mechanical computer model of the heart developed at IBT, we showed that mechano-electric feedback changes activation and repolarization patterns throughout the heart during sinus rhythm and leads to a markedly more heterogeneous electrophysiological substrate. Read the full study published open access in The Journal of Physiology.