BildInfluence of cardiac motion on the ECG

Using an electromechanical computational model, researchers at IEKM in Freiburg and IBT could quantify the effect that cardiac motion has on the ECG. This work is an important basis for faster ECG simulations in the future.

BildEP Europace cover story

A joint study of the University Heart Center Freiburg-Bad Krozingen and the IBT is featured on the cover page of the December issue of the renowned scientific journal "EP Europace". The study uses the ECG and ECGI to diagnose pathological changes in the atria.

BildAxel Loewe completes habilitation

With the colloquium "Machine Learning for Medicine and the Role of Simulated Data", Dr.-Ing. Axel Loewe qualified as a university lecturer for the field "Modeling and Simulation for Medicine".

BildPhD Mark Nothstein

The graduations season continues at IBT. We are very proud to announce that Mark Nothstein has successfully defended his PhD thesis: "Characterizing Atrial Fibrillation Substrate by Electrogram and Restitution Analysis”. Look what a nice hat his colleagues have made for him!

BildPhD Steffen Schuler

Last week, Steffen Schuler from our group successfully defended his thesis “Novel Methods to Incorporate Physiological Prior Knowledge into the Inverse Problem of Electrocardiography” Congratulations to our newest PhD! #phdlife #CardioTwitter.

BildDirected Graph Mapping for Atrial Flutter

IBT researchers in the MY-ATRIA consortium have published a new method to better characterize atrial flutter. The approach makes use of graph-theoretical methods.

ImageAmerican Heart Association Meeting

Claudia Nagel participated at the Cardiac Physiome Workshop and at the annual meeting of the American heart association. She presented her latest results regarding the influence of the ventricular shape on simulated QRS complexes in the ECG and showed that an estimation of the left atrial fibrotic volume fraction based on simulated P waves was possible with an average error of 8.7%.

BildIBT at BMT

20 employees and students of IBT attended this year's annual meeting of the German society of biomedical engineering. 9 presentations and 3 posters from the three research groups were held and presented. Congratulations to Giorgio Luongo for winning the 2nd price for patient safety and to Hannes Welle for the 2nd place in the student competition.

BildVirtual Metrology Meeting (VirtMet)

Olaf Dössel and Claudia Nagel participated in the first international workshop on metrology for virtual measuring instruments. Olaf Dössel held a keynote lecture about digital twins in medicine and Claudia Nagel talked about how fidelity of simulated ECGs can be assessed for a successful and meaningful application of simulated signals to clinical use cases.

BildWorkshop on Statistical Atlases and Computational Modeling of the Heart (STACOM)

Claudia Nagel presented her work at the workshop for Statistical Atlases and Computational Modeling of the Heart (STACOM). In her presentation, she talked about an application of the bi-atrial statistical shape model developed at IBT for identifying left atrial enlargement with the 12-lead ECG.

BildAtrial Signals conference

The biannual Atrial Signals conference convened at KIT in September. More than 200 experts from both engineering and clinical communities joined discussions and presented the latest research.

BildAward for Patient Safety in Biomedical Engineering 2021

Let's congratulate our colleague Giorgio Luongo and the whole team for winning the second prize for the patient safety in biomedical engineering 2021 with the publication “Machine learning enables noninvasive prediction of atrial fibrillation driver location and acute pulmonary vein ablation success using the 12-lead ECG”. The award was handed in occasion of the BMT 21 conference in Hannover, and offered by the German Society of Biomedical Engineering (DGBMT).

BildNew research scholarship holder at IBT

We welcome Miriam Weiß as a new research scholarship holder in the group "Optical Technologies in Medicine".

Image Konsistente biventrikuläre KoordinatenCobiveco: Consistent biventricular coordinates

IBT researchers have published an improved ventricular coordinate system for localization, data mapping and regression on cardiac geometries. An open MATLAB implementation of the method for precise and intuitive description of position in the heart is available for the community.
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Bild SIL LogoApply now for the Student Innovation Lab 2021/2022!

Have you ever dreamed of your own startup? Have you ever been curious about realizing your own product idea? – Then, the Student Innovation Lab is your place to go! Make the new ‘Computer Vision for Health’ Lab by Zeiss and IBT your think tank!
Experience the complete startup process from ideation and prototyping to the pitch in front of potential investors. 
2 terms, 15 ECTS (Economics: 18 ECTS), application until October 10th here! 

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Logo The CarpentriesSoftware Carpentry Workshop at KIT

On October 28th and 29th 2021, the Institute of Biomedical Engineering is hosting a workshop which aims at teaching foundational coding to researchers, open to registration for all KIT members.

BildStatistical Shape Model of the Atria

Claudia Nagel, Steffen Schuler, Olaf Dössel and Axel Loewe published a paper on a bi-atrial statisical shape model. The model includes the anatomical shape variations of the atria in the study population and was analyzed with standard evaluation criteria. The shape model and 100 exemplary atrial geometries suitable for electrophysiological simulations are openly available online.

Logo de-RSE e.V.Research Software - Sustainable Development and Support

IAMO Policy Brief 42 focuses on the needs and strategies for sustainable research software practices based on a position paper.

hearts-logoReview article on the calculation of the ECG with the help of computer models of the heart published

Olaf Dössel, Giorgio Luongo, Claudia Nagel and Axel Loewe have written a review article that deals with the calculation of the ECG from computer models of the heart. Both the healthy heart and simulations of various heart diseases are considered. It becomes clear how computer modeling can contribute to a better interpretation of the EKG.

BildMechanisms of hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy impairs cardiac mechanics but the differential effects of a thicker wall, reduced active force, fiber disarray and increased tissue stiffness are not clear. IBT researchers could elucidate their contribution to deformation, strain, strain rate and wall thickening using a computational model of the heart.

iHeart 2021iHeart conference 2021

During the iHeart conference from July 1-3, about 200 participants virtually presented and discussed their research. The IBT was successfully involved with two presentations.

BildPromotion Ekaterina Kovacheva

On the 8th of July Ekaterina Kovacheva completed her PhD with the title “Model Based Estimation of the Elastomechanical Properties of the Human Heart.” Congratulations from everyone at IBT.

BildDoctorate Jorge Sanchez

Congratulations to Jorge Patricio Sanchez Arciniegas on the completion of his PhD and the beginning of his work at IBT as a postdoc.

Image personalized heartComputer Model of a personalized heart

In cooperation with the IANM (KIT) and the IEKM (University Heart Center Freiburg), researchers at IBT proposed an electro-mechanically coupled computer model of a personalized human heart. The manuscript was published in the Journal Mathematics.

BildTransit Time Measurement in Indicator Dilution Curves

Researchers at IBT investigated how accurate a transit time measurement of an indicator bolus can be and proposed methods to enhance the accuracy. The work was published in the  Frontiers in Physiology .

Image graphical abstractNumber of cameras for the 3D reconstruction

Researchers at IBT investigated how many cameras are needed so that a microsurgical operating channel can be reconstructed as completely as possible in 3D.
The work was published in the Journal of Imaging (MDPI):

EHRA Congress 2021

A scientist of the IBT presented and discussed their research titled: “Spatial and Quantitative Assessment of the Correlation between Sinus Rhythm and Atrial Fibrillation Voltage Mapping to Identify Low Voltage Substrate in Persistent Atrial Fibrillation“ at this years EHRA congress. The congress was held online from the 23-25th of April, with this years' scientific program emphasising “Making connections to overcome arrhythmia”.

CombinationsEstimation of Atrial Fibrosis with the ECG

Researchers at IBT investigated whether the amount of diseased fibrotic tissue in the atria can be estimated non-invasively and quantitatively with features extracted from P waves of the 12-lead ECG.
The work was published in the Journal of Clinical Medicine (MDPI).

Girlsday_MedizintechnikGirls’ Day 2021

Der Workshop des IBT im Rahmen des Girls‘ Day 2021 traf auf großes Interesse des weiblichen Nachwuchses in den Bereichen Medizin und Technik.

Portrait von Simon HoffmannSimon Hoffmann will be research assistant at IBT

We welcome Mr. Simon Hoffmann as a research assistant. His work will focus on data processing in ophthalmology.

Portrait von Marie HouillonNew research assistant at IBT

Since April 1st, 2021 Dr. Marie Houillon is new research assistant in the computational cardiac modeling group at IBT.

BildNon invasive prediction of atrial fibrillation driver location

IBT researcher Giorgio Luongo and colleagues presented a machine learning-based classification of 12-lead ECG to discriminate between patients with pulmonary vein drivers vs. those with extra-pulmonary vein drivers of atrial fibrillation.
The paper is published in the Cardiovascular Digital Health Journal.

Transmembrane potentialProtocol to Assess Arrhythmia Vulnerability

Researchers at IBT showed the influence of the chosen protocol to induce arrhythmia on the assessment of atrial fibrillation vulnerability.

The paper was published in Frontiers of Physiology and is freely available.

Bild Herzmodellierung 2021Computational hearts for success of therapy

KIT's Institute of Biomedical Engineering develops, based on mathematical equations, a computational heart model to enable targeted therapy of cardiac arrhythmias. The model supports medical research and development in the fields of diagnostic and therapeutic approaches.

Bild zur Kraft RekonstruktionEstimating Cardiac Active Tension from Wall Motion - An Inverse Problem of Cardiac Biomechanics

IBT researches have published a paper, which presents a model-based method for solving an inverse problem of the heart biomechanics.

Bild RefraktärzeitCycle Length Statistics during ongoing Atrial Fibrillation Yield Refractory Measure

Researchers at IBT showed that the statistical analysis of cycle lengths during atrial fibrillation allows to estimate refractory periods of the underlying substrate. The study combines a broad set of simulations with clinical acquisitions and was published in Europace EP.

Bild Nicolas PiliaGraduation Nicolas Pilia

Nicolas Pilia defended his dissertation „Electrocardiogram Signal Analysis and Simulations for Non-Invasive Diagnosis - Model-Based and Data-Driven Approaches for the Estimation of Ionic Concentrations and Localization of Excitation Origins“ on February 18th 2021 and graduated with distinction. Congratulations!

BildWhitepaper on sustainable development of research software in Germany

The Paper describes the environment for the development of sustainable research software in Germany, identifies challenges and calls for action.

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