BildStatistical Shape Model of the Atria

Claudia Nagel, Steffen Schuler, Olaf Dössel and Axel Loewe published a paper on a bi-atrial statisical shape model. The model includes the anatomical shape variations of the atria in the study population and was analyzed with standard evaluation criteria. The shape model and 100 exemplary atrial geometries suitable for electrophysiological simulations are openly available online.

Logo de-RSE e.V.Research Software - Sustainable Development and Support

IAMO Policy Brief 42 focuses on the needs and strategies for sustainable research software practices based on a position paper.

hearts-logoReview article on the calculation of the ECG with the help of computer models of the heart published

Olaf Dössel, Giorgio Luongo, Claudia Nagel and Axel Loewe have written a review article that deals with the calculation of the ECG from computer models of the heart. Both the healthy heart and simulations of various heart diseases are considered. It becomes clear how computer modeling can contribute to a better interpretation of the EKG.

BildMechanisms of hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy impairs cardiac mechanics but the differential effects of a thicker wall, reduced active force, fiber disarray and increased tissue stiffness are not clear. IBT researchers could elucidate their contribution to deformation, strain, strain rate and wall thickening using a computational model of the heart.

iHeart 2021iHeart conference 2021

During the iHeart conference from July 1-3, about 200 participants virtually presented and discussed their research. The IBT was successfully involved with two presentations.

BildPromotion Ekaterina Kovacheva

On the 8th of July Ekaterina Kovacheva completed her PhD with the title “Model Based Estimation of the Elastomechanical Properties of the Human Heart.” Congratulations from everyone at IBT.

BildDoctorate Jorge Sanchez

Congratulations to Jorge Patricio Sanchez Arciniegas on the completion of his PhD and the beginning of his work at IBT as a postdoc.

Image personalized heartComputer Model of a personalized heart

In cooperation with the IANM (KIT) and the IEKM (University Heart Center Freiburg), researchers at IBT proposed an electro-mechanically coupled computer model of a personalized human heart. The manuscript was published in the Journal Mathematics.

BildTransit Time Measurement in Indicator Dilution Curves

Researchers at IBT investigated how accurate a transit time measurement of an indicator bolus can be and proposed methods to enhance the accuracy. The work was published in the  Frontiers in Physiology .

Image graphical abstractNumber of cameras for the 3D reconstruction

Researchers at IBT investigated how many cameras are needed so that a microsurgical operating channel can be reconstructed as completely as possible in 3D.
The work was published in the Journal of Imaging (MDPI):

EHRA Congress 2021

A scientist of the IBT presented and discussed their research titled: “Spatial and Quantitative Assessment of the Correlation between Sinus Rhythm and Atrial Fibrillation Voltage Mapping to Identify Low Voltage Substrate in Persistent Atrial Fibrillation“ at this years EHRA congress. The congress was held online from the 23-25th of April, with this years' scientific program emphasising “Making connections to overcome arrhythmia”.

CombinationsEstimation of Atrial Fibrosis with the ECG

Researchers at IBT investigated whether the amount of diseased fibrotic tissue in the atria can be estimated non-invasively and quantitatively with features extracted from P waves of the 12-lead ECG.
The work was published in the Journal of Clinical Medicine (MDPI).

Girlsday_MedizintechnikGirls’ Day 2021

Der Workshop des IBT im Rahmen des Girls‘ Day 2021 traf auf großes Interesse des weiblichen Nachwuchses in den Bereichen Medizin und Technik.

Portrait von Simon HoffmannSimon Hoffmann will be research assistant at IBT

We welcome Mr. Simon Hoffmann as a research assistant. His work will focus on data processing in ophthalmology.

Portrait von Marie HouillonNew research assistant at IBT

Since April 1st, 2021 Dr. Marie Houillon is new research assistant in the computational cardiac modeling group at IBT.

BildNon invasive prediction of atrial fibrillation driver location

IBT researcher Giorgio Luongo and colleagues presented a machine learning-based classification of 12-lead ECG to discriminate between patients with pulmonary vein drivers vs. those with extra-pulmonary vein drivers of atrial fibrillation.
The paper is published in the Cardiovascular Digital Health Journal.

Transmembrane potentialProtocol to Assess Arrhythmia Vulnerability

Researchers at IBT showed the influence of the chosen protocol to induce arrhythmia on the assessment of atrial fibrillation vulnerability.

The paper was published in Frontiers of Physiology and is freely available.

Bild Herzmodellierung 2021Computational hearts for success of therapy

KIT's Institute of Biomedical Engineering develops, based on mathematical equations, a computational heart model to enable targeted therapy of cardiac arrhythmias. The model supports medical research and development in the fields of diagnostic and therapeutic approaches.

Bild zur Kraft RekonstruktionEstimating Cardiac Active Tension from Wall Motion - An Inverse Problem of Cardiac Biomechanics

IBT researches have published a paper, which presents a model-based method for solving an inverse problem of the heart biomechanics.

Bild RefraktärzeitCycle Length Statistics during ongoing Atrial Fibrillation Yield Refractory Measure

Researchers at IBT showed that the statistical analysis of cycle lengths during atrial fibrillation allows to estimate refractory periods of the underlying substrate. The study combines a broad set of simulations with clinical acquisitions and was published in Europace EP.

Bild Nicolas PiliaGraduation Nicolas Pilia

Nicolas Pilia defended his dissertation „Electrocardiogram Signal Analysis and Simulations for Non-Invasive Diagnosis - Model-Based and Data-Driven Approaches for the Estimation of Ionic Concentrations and Localization of Excitation Origins“ on February 18th 2021 and graduated with distinction. Congratulations!

BildWhitepaper on sustainable development of research software in Germany

The Paper describes the environment for the development of sustainable research software in Germany, identifies challenges and calls for action.

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