News 2025
Teilnehmer bei der Helmholtz AI Conference 2025 in Karlsruhe.Helmholtz AI Conference 2025

Our group recently attended the Helmholtz AI Conference 2025 in Karlsruhe. It was a highly insightful event, emphasizing critical advancements in AI for science, including foundational models, agentic AI, and energy consumption. Silvia and Julian presented their research via posters (PSII-43 and PSII-46), sparking valuable discussions. This conference offered a crucial opportunity to engage with the AI community and gather new perspectives for our work.

Person hält Vortrag über das Extrazellular-Membran-Intrazellular-Modell.Coupled Problems Conference in Sardinia

From 25 to 28 May, the Coupled Problems conference took place in Villasimius, Sardinia. Our institute was represented there by Joshua, who presented a convergence analysis of spatial discretisation for meshes with explicitly represented cardiac cells. The aim was to reduce simulation runtimes based on the Extracellular-Membrane-Intracellular (EMI) model by deliberately coarsening the mesh resolution – without compromising the significance of the results.

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Image91. DGK – Annual Conference

From April 23–26, the 91st Annual Meeting of the German Society of Cardiology (DGK) took place in Mannheim. Joshua and Silvia presented posters on their latest research (pacing frequency dependence of cardiac excitation conduction via fibroblasts and non-invasive atrial cardiomyopathy diagnosis), while Christian gave a talk on the automatic division of bi-atrial geometries. Pascal and Axel also attended, connecting with the cardiology research community.

ImageAdvances and Challenges in Computational Modelling

Since the turn of the millennium, computational modelling of biological systems has evolved remarkably. The article highlights recent achievements and new challenges, particularly in the cardiovascular system. It emphasizes the importance of mechanistic and data-driven models and their synergies to foster future progress in medical research and artificial intelligence.

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ImageEHRA 2025 in Vienna

From March 30 to April 1, the annual meeting of the European Heart Rhythm Association (EHRA) took place, bringing together scientists, healthcare professionals, and key stakeholders from around the world involved in arrhythmia management. Axel Loewe and Silvia Becker represented the IBT at the event. Additionally, Silvia gave a presentation on why it matters how the P-wave is measured in the ECG.

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ImageAdvancing PVC Localization: A New Approach with ECGI and Digital Twins

Accurately identifying the origin of premature ventricular contractions (PVCs) is crucial for improving diagnosis and treatment. Read more about this innovative approach led by a collaborative research team, including contributions from CaMo IBT.

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Eine Präsentation über digitale Zwillinge und Herzmodellierung.E-Science Days in Heidelberg

From March 12 to 14, the E-Science Days took place in Heidelberg with the theme “Research Data Management: Challenges in a Changing World.” Axel Loewe and Silvia Becker represented the IBT in the workshop “Information Infrastructures in the Era of Artificial Intelligence: Opportunities and Challenges,” organized by the Leibniz ScienceCampus DiTraRe. Additionally, Silvia Becker, together with Lea Singson from FIZ Karlsruhe, gave a presentation on the legal aspects of digital twins and synthetic ECGs.

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c'tSupercomputers simulate patients' hearts with highly scalable algorithms

Numerical simulation makes it possible to model very different processes, from the weather to nuclear fusion to individual body organs. This requires highly scalable algorithms that can be put together from a mathematical library like a construction kit.
An article in the current issue of c't Magazine für Computertechnik reports on the research at KIT's Institute of Biomedical Engineering and collaborators.

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<Text wird generiert, bitte warten...>New Insights on Sinoatrial Node Pacemaking Mechanisms

A new paper investigating the interactions between reduced extracellular calcium levels and sympathetic stimulation as a compensatory mechanism, potentially contributing to sudden cardiac death in chronic kidney disease patients, has been published in the Journal of Physiology.

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Cardiac Arrhythmia Mechanisms GRCGRS/GRC 2025 in Barga

The Gordon Research Seminar and on Cardiac Arrhythmia Mechanisms was held in Barga from February 22 to 27. It covered a wide range of topics, from atrial and ventricular mechanisms to micro- and ultrastructures of individual cardiac muscle cells. Christian, Moritz, and Axel (on behalf of Tobias) presented their work.

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ImageCredibility Assessment of Machine Learning Predictors

Our recent publication "Consensus Statement on the Credibility Assessment of Machine Learning Predictors" in the journal Briefings in Bioinformatics aims to ensure the reliability and credibility of machine learning models used in clinical and biomedical contexts. Together with other leading experts, we outline a structured framework based on 12 foundational statements and propose rigorous guidelines for evaluating and enhancing the credibility of ML predictors, particularly when used in high-stakes healthcare decisions.

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ImageSuccessful Doctoral Defense: Dr.-Ing. Cristian Barrios Espinosa at KIT

Dr.-Ing. Cristian Barrios Espinosa successfully defended his doctoral thesis at KIT, advancing Eikonal-based models to improve the accuracy and efficiency of cardiac electrophysiology simulations.

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ImageNews of DREAM

A new paper introduces the latest version of the DREAM for simulating cardiac arrhythmias. Published in Engineering with Computers, it provides an efficient approach to reentry simulations in cardiac electrophysiology.
Read the full paper here.

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