Engineering for Health
Welcome to the web page of the Institute of Biomedical Engineering (IBT) at Karlsruhe Institute of Technology (KIT). For more than 50 years we have been active in research and teaching in the field of biomedical engineering.
In interdisciplinary projects together with medical doctors and medical industry, we investigate new technical systems that help to diagnose diseases earlier and more accurately as well as systems that make therapies more successful.
The main focus of the research program of Prof. Dr. Werner Nahm's group is optical systems in medicine and life sciences. Current projects are focussing on surgical visualization and optical diagnosis [more].
The group of PD Dr. Axel Loewe develops computational models of the heart and applies them to cardiological problems. We focus on cardiac electrophysiology and elastomechanics to contribute to answer clinical questions such as the genesis of e.g. cardiac arrhythmias and appropriate treatment strategies [more].
The main focus of the research program of Prof. Dr. Olaf Dössel was the analysis of biosignals from the heart (ECG and electrograms) and the imaging of electrophysiological sources in the heart (ECG imaging) [more].
As a contribution to the FIMH conference, using simulations, we investigated abnormal excitation patterns in the atrium and their electrograms. In contrast to existing studies, we here considered the curvature, different wall thicknesses, as well as electric heterogeneity in a realistic right-atrial geometry.
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Together with researchers from the Medical University of Graz, PTB Berlin and King's College London, we have published a dataset of 16,900 synthetic ECGs. The ECGs have been generated by detailed computer simulations that allow each ECG signal to be traced back to unique model parameters with biological meaning.
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Extra heartbeats from the main chambers of the heart, so-called ventricular extrasystoles, can be related to serious diseases. Researchers at the Karlsruhe Institute of Technology (KIT) use machine learning to determine the origin of the extrasystoles non-invasively.
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The IBT and Prototera Association (Portugal) established an agreement for 4-year PhD fellowships funded by the Portuguese Government. Students who are interested in doctoral research projects in the field of Image Guidance in Proton Therapy can contact Prof. Francesca Spadea mf.spadea@kit.edu. The 4 year project will be conducted in joint collaboration with the University “Instituto Superior Técnico” of Lisbon.
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Our latest paper describes a methodology to generate anatomical and functional atrial digital twins personalized models from imaging data and/or electroanatomical maps.
The reproducible and automated framework processes geometries derived from clinical data.
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Together with physicians from the University Heart Center Freiburg Bad Krozingen, we compared whether substrate underlying atrial fibrillation can be localized not only in sinus rhythm but also during atrial fibrillation. The moderate agreement suggests to perform the investigation in sinus rhythm.
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