Engineering for Health

Welcome to the web page of the Institute of Biomedical Engineering (IBT) at Karlsruhe Institute of Technology (KIT). For more than 50 years we have been active in research and teaching in the field of biomedical engineering.

In interdisciplinary projects together with medical doctors and medical industry, we investigate new technical systems that help to diagnose diseases earlier and more accurately as well as systems that make therapies more successful.

The main focus of the research program of Prof. Dr. Olaf Dössel is the analysis of biosignals from the heart (ECG and electrograms), the imaging of electrophysiological sources in the heart (ECG imaging). Moreover, we are working on impedance tomography for lung perfusion and hypothermia in stroke patients [more].

The area of research of Prof. Dr. Werner Nahm's group is optical systems in medicine and life sciences. Current projects are focussing on surgical visualization and optical diagnosis [more].

The group of PD Dr. Axel Loewe develops computational models of the heart and applies them to cardiological problems. We focus on cardiac electrophysiology and elastomechanics to contribute to answer clinical questions such as the genesis of e.g. cardiac arrhythmias and appropriate treatment strategies [more].

News

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Hybrid machine learning to localize atrial flutter substrates using the surface 12-lead ECG

IBT former researcher Giorgio Luongo, PhD presented a hybrid machine learning-based classification of 12-lead ECG to discriminate between patients with three different kind of atrial flutter (cavotricuspidal-isthmus-dependent vs. peri-mitral vs. other left atrium atrial flutters). This novel algorithm may aid to identify non-invasively the best ablation procedure to terminate the arrhythmia prior to the invasive procedure in the EP labs. This work is the result of a successful collaboration between 5 engineering and clinical groups (Università degli Studi di Milano, University of Leicester, ABC Federal University, Städtisches Klinikum Karlsruhe and IBT). The paper is published in EP Europace journal and is freely available.

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Blood flow shows minor effects on the deformation of the healthy heart

Researchers of the IBT and the ISTM (Institute of Fluid Mechanics, KIT) have implemented a sequential coupling approach and found that the influence of the blood flow only slightly changes the deformation of the heart wall.

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Progress - first technical, then clinical

The international "Atrial Signals" congress took place for the fourth time in September 2021 under the patronage of the Karlsruhe Municipal Hospital (Prof. Dr. med. Claus Schmitt) and the Karlsruhe Institute of Technology (Prof. Dr. rer. nat. Olaf Dössel ) including synergy effects.

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ECG Imaging improved

The solution of the inverse problem for ECG imaging (ECGI) is prone to detection of artifacts. A team around IBT researcher Steffen Schuler presented a method to avoid line-of-block artifacts to improve ECGI as a noninvasive diagnostic tool.

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Influence of cardiac motion on the ECG

Using an electromechanical computational model, researchers at IEKM in Freiburg and IBT could quantify the effect that cardiac motion has on the ECG. This work is an important basis for faster ECG simulations in the future.

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EP Europace cover story

A joint study of the University Heart Center Freiburg-Bad Krozingen and the IBT is featured on the cover page of the December issue of the renowned scientific journal "EP Europace". The study uses the ECG and ECGI to diagnose pathological changes in the atria.

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