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Head of Institute:
Prof. Dr. rer. nat. Olaf Dössel 
Prof. Dr. rer. nat. Werner Nahm

Postal address:
Kaiserstr. 12
76131 Karlsruhe

Visitor / Delivery address:
Building 30.33
Fritz-Haber-Weg 1
76131 Karlsruhe

Fon: +49 721 608-42650
Fax: +49 721 608-42789
E-Mail: infoLmm5∂ibt kit edu

IBT Seminar

Mr. cand. el. Felix Schuderer:
"Optimized nonlinear modeling of indicator dilution curves in Electrical Impedance Tomography to separated cardiac and pulmonary boluses" (Bachelor thesis)
Date: 13.09.2018 2:00 p.m.

s. cand. mach. Rosa Daschner:
"Generation of a simplified brain geometry for the calculation of local cerebral temperature using a 1D-hemodynamics model" (Bachelor thesis)
Date: 13.09.2018 2:45 p.m.Place: IBT library, building 30.33, room 517

Workshop "Integrated Heart Model"


Engineering for Health

Welcome to the web page of the Institute of Biomedical Engineering (IBT) at Karlsruhe Institute of Technology (KIT). For more than 50 years we have been active in research and teaching in the field of biomedical engineering.

In interdisciplinary projects together with medical doctors and medical industry, we investigate new technical systems that help to diagnose diseases earlier and more accurately as well as systems that make therapies more successful.

The main focus of the research program of Prof. Dr. Olaf Dössel is the analysis of biosignals from the heart (ECG and electrograms), the imaging of electrophysiological sources in the heart (ECG imaging). Moreover, we are working on impedance tomography for lung perfusion and hypothermia in stroke patients [more].

The area of research of Prof. Dr. Werner Nahm's group is optical systems in medicine and life sciences. Current projects are focussing on surgical visualization and optical diagnosis [more].

The group of Dr. Axel Loewe develops computational models of the heart and applies them to cardiological problems. We focus on cardiac electrophysiology and elastomechanics to contribute to answer clinical questions such as the genesis of e.g. cardiac arrhythmias and appropriate treatment strategies [more].



New spatio-temporal method for ECG imaging

Every spread of electrical excitation in the heart creates a characteristic spatio-temporal pattern of potentials on the surface of the body.
At IBT, a new method for ECG imaging has now been developed, which utilizes this spatio-temporal relationship by representing measured body surface potentials as superposition of basic potential patterns, for which the corresponding excitation pattern is known. The novel method has been published in the journal „Frontiers in Physiology“.
It could be shown that the origin of simulated atrial extrasystoles can be reconstructed more robustly and more accurately from noisy measurement data than with a commonly used reference method.

Axel Loewe
Axel Loewe awarded third place of the Gips-Schüle young talent award 2018

Atrial fibrillation is one of the most common cardiac arrhythmias in humans and responsible for 25 percent of all strokes. Drug therapy or surgery on the heart are often ineffective in the long term.
In his dissertation, Axel Loewe from the Institute of Biomedical Engineering of KIT examines atrial fibrillation using computer models. He has succeeded in integrating individual measurement data from patients, for example the genome of the cardiovascular system, into mathematical models. The model-based approaches contribute to a broader understanding of the disease. This will allow more efficient, personalized therapies to be developed.
With his research Loewe now took third place in the Gips Schüle Foundation's Gips-Schüle Award 2018.

KIT News
Luca Azzolin
New research assistant at IBT

We would like to welcome Mr. Luca Azzolin as a research assistant at the Institute of Biomedical Engineering, started at July 1st, 2018. Within the framework of the MY-ATRIA Innovative Training Network (ITN), funded by the European Commission’s Horizon 2020 Marie Sklodowska-Curie programme, Mr. Azzolin is working in the cardiac modeling group at IBT at the development of an integrated and personalized computational model of the atria for an efficient ablation therapy for atrial fibrillation. The final expected result will be a tool helping the cardiologist to predict the ablation outcome.

Mr. Azzolin completed his Bachelor’s and Master’s degree in Computational Science and Engineering (Mathematical Engineering) at Politecnico di Milano. His research topics were focused on the electromechanical modelling and computer simulation of the human ventricles.

New research assistant at IBT

We would like to welcome Mr. Jorge Sánchez as a research assistant starting July 2018. As a member of the computational cardiac modeling group, Jorge Sánchez‘s research will focus on the development of an open source modeling framework for the electrophysiology of the heart. We aim to provide a sustainable research software of high quality and a focus on user-friendliness. This will provide an optimal solution for a large proportion of those who can potentially benefit from cardiac computer modeling methods.

New research assistant at IBT

We would like to welcome Mr. Giorgio Luongo as a research assistant at the Institute of Biomedical Engineering as of July 1st, 2018. Inside the framework of the MY-ATRIA Innovative Training Network (ITN), funded by the European Commission’s Horizon 2020 Marie Sklodowska-Curie programme, Mr. Luongo is working with the biosignals group at IBT to understand the relationship between various patterns of depolarization in the atria during Sinus Rhythm, Atrial Flutter, Atrial Fibrillation, and the corresponding 12-lead ECG as well as BSPM. Additionally, to understand which of the atrial depolarization patterns can be reliably detected, identified, or localized.

Mr. Luongo completed his Bachelor’s and Master’s degree in Clinical Engineering and Biomedical Engineering at the University of Rome “La Sapienza”. His research topics were focused on the implementation of a regularized classifier based on evoked potentials EEG signals and on the implementation of an asynchronous control for Brain Computer Interface systems.

IBT at the Interdisciplinary Cerebrovascular Symposium (ICS)

In 2018, the international conference celebrated its 15th birthday in Magdeburg, Germany. Following the conference series motto “Bringing together international PhD and MD experts”, Yannick Lutz presented his work concerning the development of a numerical model of brain and systemic temperature during local hypothermia for ischemic stroke treatment. The usage of a novel cooling catheter enables the possibility for fast local inducement of therapeutic hypothermia while reducing systemic side effects.