Engineering for Health
Welcome to the web page of the Institute of Biomedical Engineering (IBT) at Karlsruhe Institute of Technology (KIT). For more than 50 years we have been active in research and teaching in the field of biomedical engineering.
In interdisciplinary projects together with medical doctors and medical industry, we investigate new technical systems that help to diagnose diseases earlier and more accurately as well as systems that make therapies more successful.
The main focus of the research program of Prof. Dr. Werner Nahm's group is optical systems in medicine and life sciences. Current projects are focussing on surgical visualization and optical diagnosis [more].
The group of PD Dr. Axel Loewe develops computational models of the heart and applies them to cardiological problems. We focus on cardiac electrophysiology and elastomechanics to contribute to answer clinical questions such as the genesis of e.g. cardiac arrhythmias and appropriate treatment strategies [more].
The main focus of the research program of Prof. Dr. Olaf Dössel was the analysis of biosignals from the heart (ECG and electrograms) and the imaging of electrophysiological sources in the heart (ECG imaging) [more].
During April the conference of the German society of cardiology (DGK) and the European Heart Rhythm Association (EHRA) took place bringing together cardiologists from Germany and around the world. On the 7th-9th The European Heart Rhythm Association (EHRA) conference took place in Berlin. Our PhD student Patricia Martínez was nominated for the Young Investigator Award in the Basic and Translational Science category and presented her work on the effects of right atrial arrhythmia susceptibility in patient-specific computer models.
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From March 18 to March 22, 2024 the 94th annual meeting of the GAMM (Association of Applied Mathematics and Mechanics) took place in Magdeburg at the Otto von Guericke university. Our PhD student Jonathan Krauß presented a comparison of different pericardium modeling approaches.
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In this year’s Biosignals Workshop in Göttingen, we presented our work on electrograms in a cell-by-cell model. We have shown that healthy excitation propagation, as opposed to what we would expect in homogenised models, yields asymmetric electrograms exhibiting several small deflections. These deflections, in turn, can be explained by the multimodality of cell activation as well as the deceleration of the excitation wave when transitioning between two cardiac cells.
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What influence does the inclusion of the right atrium have on the assessment of arrhythmia susceptibility in patient-specific computer models? In this study, we investigated differences in arrhythmia susceptibility between monoatrial and biatrial models. Our results suggest that inclusion of the right atrium increases inducibility in the model and also shows a state-dependent influence on arrhythmia dynamics.
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A new course for Master Students will be offered since SS24 from IBT lectures. The course, titled “Medical Image Processing for guidance and navigation”, will be worth 6 ECTs for a total of 4 hours per week of lectures/practical exercises plus the accomplishment of a group project.
The language of the lecture is English.
This open access book has brought together 138 experts in In Silico Trials working in academia, the medical industry, regulatory bodies, hospitals, and consulting firms. Through a consensus process, these experts produced the first attempt to define some Good Simulation Practices on how to develop, evaluate, and use In Silico Trials. Good Simulation Practice constitutes an indispensable guide for anyone who is planning to engage at any title with In Silico Trials. IBT researcher Axel Loewe has co-edited the chapters Model Development and The Investigator: Modellers and Analysts.
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