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Tobias Oesterlein

Dr.-Ing. Tobias Oesterlein

Alumnus


Forschungsprojekte
Titel Ansprechpartner


Intracardial ECG Signal Processing / Mapping of endocardial activation patterns

Intracardial ECG Signal Processing / Mapping of endocardial activation patterns
Ansprechpartner:

Tobias Oesterlein, Olaf Dössel 

Projektgruppe:Medizinische Messtechnik &. digitale Signalverarbeitung

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Atrial Fibrillation (AFib) is the most common cardiac arrhythmia, showing an increasing prevalence with age. Hemodynamic impairment and thromboembolic events related to AFib result in significant morbidity and mortality.

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Catheter ablation, notably the electric isolation of the pulmonary veins, has become a well-established curative therapeutic approach in drug-resistant atrial fibrillation. Despite the considerable clinical experience and accumulated evidence from experimental data, the exact mechanisms behind AFib are still not completely understood. Different concepts like rotational drivers, ectopic foci or dissociation of layers are discussed controversially - together with their respective curative ablation approaches.

PRJ_2011-02-16_C_Schilling_csc_Bild_02.jpg

Together with Städtisches Klinikum Karlsruhe, we are trying to understand endocardial activity during AFib. Electrograms measured intracardially during an electrophysiological examination are analyzed with methods of signal processing and multivariate statistics. A large set of descriptors can be computed for each signal and used to classify several different types of fractionated electrograms. The spatio-temporal pattern of excitation is evaluated using simultaneous multichannel data from catheters recording in local high-density or in panoramic mode with up to 64 electrodes. Quantitative analysis helps to identify dominant mechanisms and their degree of stability. All information can be visualized on patient specific geometries and related to the atrial anatomy. This will support the physician in finding the best ablation strategy in treatment of AFib.

Recent Publications

  • T. G. Oesterlein et al. Removing ventricular far-field signals in intracardiac electrograms during stable atrial tachycardia using the periodic component analysis, Journal of Electrocardiology, 48(2), pp. 171-180, 2015
  • C. Schilling et al. Fuzzy decision tree to classify complex fractionated atrial electrograms, BMT, 2015
  • F. M. Weber et al. Wave Direction and Conduction Velocity Analysis from Intracardiac Electrograms - A Single-Shot Technique. IEEE TBME (57), 2394-2401, 2010
Abgeschlossene Arbeiten
Titel Typ Bearbeiter Betreuer
Masterarbeit

Daniel Frisch

Masterarbeit

Laura Unger

Bachelorarbeit

Michael Stritt

Studentische Forschungsarbeit

Salina Huck

Studentische Forschungsarbeit

Felix Plappert

Bachelorarbeit

Benedikt Ebener

Bachelorarbeit

Felix Plappert

Studentische Forschungsarbeit

Sophie An

Studentische Forschungsarbeit

Daniel Frisch

Masterarbeit

Franziska Schäuble

Bachelorarbeit

Salina Huck

Studentische Forschungsarbeit

Illya Grygoryev

Masterarbeit

Christian Reich

Masterarbeit

Alexander Kramlich

Bachelorarbeit

Johann Jazewitsch

Masterarbeit

Daniela Zöller

Masterarbeit

Niko Konrad

Bachelorarbeit

Julia Trächtler

Masterarbeit

Dan-Timon Rudolph

Bachelorarbeit

Daniel Frisch 

Bachelorarbeit

Fabian Schenkel

Masterarbeit

Markus Rottmann 

Studienarbeit

Tobias Oesterlein 



Veröffentlichungen


  Alle Veröffentlichungen, sortiert nach Jahren

          2017 2016 2015 2014 2013 2012 2011 [Alle]


Preise

Finalisten bei Atrial Signals 2019 in Bordeaux:
Laura Anna Unger, Tobias Oesterlein, Annika Haas, Armin Luik, Olaf Dössel
mit dem Poster "Characterizing and Localizing Zones of Critical Conduction during Atrial Tachycardia Demands Ultra-high-resolution Electroanatomical Mapping"

2. Platz, Klee-Preis der Deutschen Gesellschaft für Biomedizinische Technik (DGBMT) 2017
Tobias Oesterlein, Multichannel Analysis of Intracardiac Electrograms

Bill and Gary Sanders Poster Award, Konferenz „Computing in Cardiology“ 2017 in Rennes (Frankreich)
Axel Loewe, Emanuel Poremba, Tobias G. Oesterlein, Nicolas Pilia, Micha Pfeiffer, Olaf Doessel, Stefanie Speidel:
An Interactive Virtual Reality Environment for Analysis of Clinical Atrial Arrhythmias and Ablation Planning

2. Preis im Studentenwettbewerb, DGBMT und DGMP Jahrestagung 2017, Dresden;
M. Stritt, T. Oesterlein, S. Pollnow, A. Luik, and C. Schmitt.
Eingereichte Arbeit: Assessment of local high-density mapping for the analysis of radiofrequency ablation lesions in the left atrium.

Auszeichnung bei der Konferenz „Computing in Cardiology“ 2016 in Vancouver (Kanada)
Bill and Gary Sanders Poster Award: Joachim Greiner, Tobias Oesterlein, Gustavo Lenis, Olaf Dössel: „Virtual Reality Visualization of Arrhythmias on a Smartphone“

2. Platz im Nachwuchswettbewerb im Rahmen des Workshop "Innovationen bei der Erfassung und Analyse bioelektrischer und biomagnetischer Signale - BBS 2016" durch Gustavo Lenis, Alexander Kramlich, Tobias Oesterlein and Olaf Dössel mit dem Beitrag: "Development and Benchmarking of Activity Detection Algorithms for Intracardiac Electrograms Measured During Atrial Flutter"

Young Investigator Award im Rahmen der 41. Tagung International Congress on Electrocardiology in Bratislava, 2014.
T. G. Oesterlein, G. Lenis; A. Luik, B. Verma, C. Schmitt, O. Dössel
Eingereichte Arbeit: "Removing Ventricular Far Field Artifacts in Intracardiac Electrograms during Stable Atrial Flutter using the Periodic Component Analysis – Proof of Concept Study"

3. Preis im Studentenwettbewerb, DGBMT Jahrestagung 2014, Hannover,
T. G. Oesterlein, G. Lenis; A. Luik, C. Schmitt, O. Dössel
Eingereichte Arbeit: "Periodic component analysis to eliminate ventricular far field artifacts in unipolar atrial electrograms of patients suffering from atrial flutter"